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Research

We're transforming the treatment landscape for children with cancer and blood disorders across the country and around the world.

Funding that saves lives

Hope & Heroes raises essential funds that make advanced treatments and cutting-edge research a reality – benefitting not just the children in our care, but patients worldwide. Every year more than 260,000 children globally are diagnosed with cancer. Many of these cancers affect only children, while common adult cancers usually affect children in very different ways. In addition, national funding for cancer research overwhelmingly targets adults with only 4% designated for studying pediatric cancers. This leaves a huge funding gap for the support of childhood cancer research and treatments.

To make sure we have the most advanced treatment options, we must continually fund research that will lead to more choices and more therapies. Our support puts Columbia University Medical Center at the forefront of investigating pediatric cancer and blood disorders, allowing us to do our very best for today’s patients while making new breakthroughs possible for the patients of tomorrow.

The future of cancer treatment—right here in New York City

Columbia’s Division of Pediatric Oncology, Hematology and Stem Cell Transplantation is an international leader in its field, constantly innovating to discover new treatment approaches even as it searches for cures. Doctors and researchers are working in the laboratory and the clinic—and bridging the two—to accelerate the pace of progress. Their work spans the spectrum with a goal of understanding and developing more effective treatments.

We know that when we fund research, we also advance care. Because discoveries in the lab related to biology, disease origins and treatment options help to inform practice in the clinic, and vice versa. What our doctors learn from their patients can guide future investigations in the laboratory.

Here are a few examples of the projects our researchers are pursuing:

  • The PCF Developmental Therapeutics Program, one of only 21 programs of its type in the country—and the only one in the tri-state area—provides the newest drugs for hard to treat diseases as well as access to the newest cancer therapies through enrollment in early-phase clinical trials.
  • The Precision in Pediatrics research program uses whole-genome analysis to customize treatment for each patient, allowing clinicians to identify the most effective and least invasive options.
  • In the WOLF Foundation Leukemia/Lymphoma Laboratory, doctors are searching for a deeper understanding of the molecular mechanisms that promote and sustain the growth and survival of leukemic cells.
  • At the Brain and Nervous System Tumor Laboratory, scientists are exploring cell growth and differentiation for brain and nervous system tumors.
  • Through the Tay-banz Solid Tumor Laboratory, researchers are exploring the biology of pediatric solid tumors through investigations of tumor blood vessel growth.
  • The Center for Survival Wellness is leading projects related to survival and long-term effects of cancer treatment like fertility and risk of heart disease.

 

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